Cloning And Mutagenesis Market by Product (Mutagenesis Kits, Cloning Kits), Technology (Site-directed Mutagenesis, Blunt End Cloning), End User (Academic & Research Institutes, Biopharmaceutical & Pharmaceutical Companies), and by Region - Global Forecast to 2022-2033

The cloning and mutagenesis market size is estimated to be USD 2,678.1 million in 2022 and is expected to witness a CAGR of 18.99% during the forecast period 2023-2033. Increasing emphasis on protein engineering for medicine discovery and rising consumer demand for crops and other products that are genetically engineered are factors contributing to the market growth. Furthermore, growing demand for individualized medicine and surge in demand for personalized medicine is expected to support the market growth. However, high price of kits is expected to hinder the growth.

Increasing emphasis on protein engineering for medicine discovery is expected to propel the market growth during the forecast period. The fundamental techniques used in protein engineering during drug development include cloning and mutagenesis. These methods support the development of therapeutic proteins by enabling the insertion, deletion, or replacement of nucleotides in protein sequences. Additionally, these methods encourage the development of affordable, more easily accessible, and safer medications. For instance, the FDA has currently approved more than 200 peptide and protein drugs.

Rising consumer demand for crops and other products that are genetically engineered is predicted to fuel the market growth during the projected period. Insect-resistant and herbicide-tolerant seeds that have undergone genetic modification have become extremely popular, and crops have easily adapted to them, supporting in the expansion of the agricultural sector. Cloning and mutagenesis have made it possible to modify crops’ genetic structure, increase soil production, and effectively fight pests. For instance, the Genetic Engineering Appraisal Committee (GEAC) approved the commercial release of GM mustard in October 2022. This initiative is anticipated to spur crop development to meet dietary needs.

Segmentation

By Product

The market is categorized into mutagenesis kits, cloning kits, others. In 2022, the cloning kits segment accounted for the highest revenue share due to the fact that cloning kits are used in a variety of fields, including biopharmaceuticals, gene therapy, and gene analysis. These kits are commonly used in the biopharmaceutical sector to produce human proteins with biological uses. To treat and prevent strokes, tissue plasminogen activator (tPA) is employed. Similar to this, cloning kits are employed in gene analysis to create recombinant and synthetic versions of genes that aid biologists in understanding the role of the normal gene in an organism’s function. Thus, the use of these kits in the biotechnology industry is projected to fuel segment growth over the course of the forecast period. The mutagenesis kits are expected to expand at the fastest rate over the projected period. Mutagenesis kits are used to clone DNA, analyze the impact of mutagens, and design proteins. Additionally, these kits are used in medical settings to treat and research conditions including cancer and HIV, and to assist individuals who are immunocompromised. As a result, the market is being driven by the growing use of mutagenesis kits in biomedical research, which is boosting kit usage in R&D activities.

By Technology

The market is categorized into site-directed mutagenesis, blunt end cloning, topo PCR cloning, seamless cloning, and others. In the global market, the topo PCR cloning segment accounted for the largest revenue share in 2022 owing to benefits of this method over competing alternatives are encouraging TOPO PCR cloning applications across a variety of end-users, including pharmaceutical and biopharmaceutical companies and academic and research institutes. This method uses DNA topoisomerase I’s biological activity to clone DNA fragments into particular vectors. This approach has a number of benefits, including high efficiency relative to conventional TA cloning, ligation and restriction-free cloning, straightforward primer design, and no need for post-PCR operations. The site-directed mutagenesis is expected to grow at the fastest rate during the projected period. A gene’s DNA sequence can be intentionally and precisely modified through the application of site-directed mutagenesis technology. This technology has applications in genetic research, gene technology, and protein engineering due to its ability to precisely modify genes and proteins. Furthermore, leading market companies are offering new site-directed mutagenesis-based kits that streamline and accelerate the process.

By End User

The market is segmented into academic & research institutes, biopharmaceutical & pharmaceutical companies, CROs & CMOs. In 2022, the segment accounted for the largest revenue share owing to increasing incidence of diseases, pharmaceutical and biopharmaceutical companies are concentrating on drug discovery and development. The therapeutic manipulation of disease-associated genes is facilitated by the use of cloning and mutagenesis techniques. In the preclinical stage of drug discovery, cloning is most appropriate for pharmacologic compounds. Growth hormone, erythropoietin, synthetic insulin, and vaccination are examples of successful therapeutic products derived through cloning. Furthermore, by providing new cells for tissue engineering and transplantation, these methods have a considerable impact on human therapies. The segment is driven by the pharmaceutical and biopharmaceutical industries’ extensive use of cloning and mutagenesis. The CROs and CMOs are expected to exhibit the fastest growth. For a number of reasons, pharmaceutical and biopharmaceutical companies are outsourcing cloning and mutagenesis to CROs and CMOs. These outsourcing strategies can result in time savings and increased output. Pharmaceutical and biopharmaceutical companies can get cloning and mutagenesis services from a number of CROs and CMOs.

Regional Markets

In 2022, North America region accounted for the highest revenue in the cloning and mutagenesis market and is expected to maintain its dominance during the forecast period. This is attributed to the rising demand for biotechnology methods. Additionally, the region’s increasing acceptance of platforms based on genomic and proteomic data has increased the use of cloning and mutagenesis techniques. The presence of leading innovators and market participants has resulted in greater product penetration in the area. For instance, the U.S. company Telesis Bio, Inc. announced in May 2021 that its BioXp technology currently supports long fragment cloning. With the aid of this initiative, researchers can create multivariant, error-corrected vectors and clone into custom vectors hand-free overnight. The Asia Pacific market is anticipated to expand at the fastest rate due to the region’s increasing demand for novel therapeutics. Additionally, a stronger economy, excessive government investment in R&D, and rapid infrastructure development are some of the drivers driving regional growth. Furthermore, funding is being provided to a number of local players to work on creating a treatment for a number of chronic diseases, including cancer. For instance, Immuneel Therapeutics raised USD 15 million in series A funding in June 2022 in order to provide a low-cost gene and cell therapy for cancer patients in India. Such initiatives in this region are projected to fuel market expansion during the research period.

Competitor Insights

Some of the key players operating in the cloning and mutagenesis market are Jena Bioscience GmbH, Thermo Fisher Scientific, Inc., New England Biolabs, Merck KGaA, Promega Corporation, Bio-Rad Laboratories, Inc., Assay Genie, Takara Bio Inc., Agilent Technologies, Inc., Danaher, and TransGen Biotech Co., Ltd.

To achieve a competitive edge, these companies are implementing a variety of growth strategies. Strategic partnerships, alliances, and agreements with different businesses and research institutions are seen to be the main strategies used by companies in this sector.

  • For instance, Takara Bio, Inc. announced in February 2022 that it would be extending its manufacturing facility, the Center for Gene and Cell Processing in Japan.

This comprehensive research report focuses on the global and regional market size and forecasts of diverse segments including product, technology, and end user from 2023 to 2033.

Report Scope:

Key Parameters Details
Market size in 2022
  • USD 2,678.1 Million
CAGR
  • 18.99%
Base Year
  • 2022
Forecast Period
  • 2023-2033
Study Coverage
  • Global and regional market size and revenue forecast
  • Segment market size and revenue forecast at global, regional, and country level
  • Competitive landscape (company share analysis, company profiles, recent development, competitive map analysis)
  • Conclusion and recommendations
Qualitative Analysis
  • Market drivers
  • Market restraints
  • Market opportunities
  • Recent market trends
  • Market challenges
  • Porter’s Five Forces analysis
  • PEST analysis
  • COVID-19 impact analysis
Segment Market Scope
  • Product
  • Technology
  • End user
Regional Market Scope
  • North America
    (U.S. and Canada)
  • Europe
    (Germany, France, UK, Spain, Italy, Russia, Rest of Europe)
  • Asia Pacific
    (China, Japan, India, Australia, South Korea, Rest of APAC)
  • Latin America
    (Brazil, Mexico, Argentina, Rest of LATAM)
  • MEA
    (South Africa, GCC, Rest of MEA)
Company Profiles
  • Exhaustive profiles of top 10 players
  • Other major players listing
15% Free Customization Available
  • You can customize the study scope to meet your exact requirement. Click here for more details

Segmentation: Cloning And Mutagenesis Market Report 2022 – 2033

Product (Revenue, USD Million), 2022 – 2033

  • Mutagenesis Kits
  • Cloning Kits
  • Others

Technology (Revenue, USD Million), 2022 – 2033

  • Site-directed Mutagenesis
  • Blunt End Cloning
  • Topo PCR Cloning
  • Seamless Cloning
  • Others

End user (Revenue, USD Million), 2022 – 2033

  • Academic & Research Institutes
  • Biopharmaceutical & Pharmaceutical Companies
  • CROs & CMOs

By Region (Revenue, USD Million), 2022 – 2033

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • France
    • UK
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of APAC
  • Latin America
    • Brazil
    • Mexico
    • Argentina
    • Rest of LATAM
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • Rest of MEA

Table of Contents: Cloning And Mutagenesis Market 2022-2033

  1. Research Methodology
    1. Study Objectives
    2. Study Scope
    3. Research Framework
      1. Research Models
        1. Bottom-up Approach
        2. Top-down Approach
        3. Data Triangulation
      2. Data Analysis
        1. Data Validation
        2. Market Size Estimation
        3. Market Forecast Model
  1. Introduction: Cloning And Mutagenesis
  2. Executive Summary
  3. Market Dynamics
    1. Market Drivers
      1. Driver 1
      2. Driver 2
      3. Driver 3
      4. Driver 4
    2. Market Restraint
      1. Restraint 1
      2. Restraint 2
      3. Restraint 3
    3. Market Opportunities
      1. Opportunity 1
      2. Opportunity 2
      3. Opportunity 3
    4. Market Trends
      1. Trend 1
      2. Trend 2
      3. Trend 3
    5. Market Challenges
      1. Challenge 1
      2. Challenge 2
      3. Challenge 3
  1. Market Environment Analysis
    1. Porter’s 5 Forces Analysis
    2. PESTEL Analysis
    3. SWOT Analysis
  2. COVID-19 Impact Analysis: Cloning And Mutagenesis Market
  3. Market Analysis by Product
    1. Mutagenesis Kits
      1. Mutagenesis Kits Market Forecast, 2022-2033(USD Million)
    2. Cloning Kits
      1. Cloning Kits Market Forecast, 2022-2033(USD Million)
    3. Others
      1. Others Market Forecast, 2022-2033(USD Million)
  1. Market Analysis by Technology
    1. Site-directed Mutagenesis
      1. Site-directed Mutagenesis Market Forecast, 2022-2033(USD Million)
    2. Blunt End Cloning
      1. Blunt End CloningMarket Forecast, 2022-2033 (USD Million)
    3. Topo PCR Cloning
      1. Topo PCR CloningMarket Forecast, 2022-2033 (USD Million)
    4. Seamless Cloning
      1. Seamless Cloning Market Forecast, 2022-2033(USD Million)
    5. Others
      1. Others Market Forecast, 2022-2033(USD Million)
  1. Market Analysis by End User
    1. Academic & Research Institutes
      1. Academic & Research Institutes Market Forecast, 2022-2033(USD Million)
    2. Biopharmaceutical & Pharmaceutical Companies
      1. Biopharmaceutical & Pharmaceutical Companies Market Forecast, 2022-2033(USD Million)
    3. CROs & CMOs
      1. CROs & CMOs Market Forecast, 2022-2033(USD Million)
  1. Regional Market Analysis
    1. Regional Market Trends Analysis
  2. North America Cloning And Mutagenesis Market
    1. North America Cloning And Mutagenesis Market
      1. North America Market Size and Forecast, 2022-2033(USD Million)
        1. Market Size and Forecast by Product, 2022-2033(USD Million)
        2. Market Size and Forecast by Technology, 2022-2033(USD Million)
        3. Market Size and Forecast by End User, 2022-2033(USD Million)
      2. S. Cloning And Mutagenesis Market
        1. S. Market Size and Forecast, 2022-2033(USD Million)
          1. Market Size and Forecast by Product, 2022-2033(USD Million)
          2. Market Size and Forecast by Technology, 2022-2033(USD Million)
          3. Market Size and Forecast by End User, 2022-2033(USD Million)
        2. Canada Cloning And Mutagenesis Market
          1. Canada Market Size and Forecast, 2022-2033(USD Million)
            1. Market Size and Forecast by Product, 2022-2033(USD Million)
            2. Market Size and Forecast by Technology, 2022-2033(USD Million)
            3. Market Size and Forecast by End User, 2022-2033(USD Million)
  1. Europe Cloning And Mutagenesis Market
    1. Europe Cloning And Mutagenesis Market
      1. Europe Market Size and Forecast, 2022-2033(USD Million)
        1. Market Size and Forecast by Product, 2022-2033(USD Million)
        2. Market Size and Forecast by Technology, 2022-2033(USD Million)
        3. Market Size and Forecast by End User, 2022-2033(USD Million)
      2. Germany Cloning And Mutagenesis Market
        1. Germany Market Size and Forecast, 2022-2033(USD Million)
          1. Market Size and Forecast by Product, 2022-2033(USD Million)
          2. Market Size and Forecast by Technology, 2022-2033(USD Million)
          3. Market Size and Forecast by End User, 2022-2033(USD Million)
        2. UK Cloning And Mutagenesis Market
          1. UK Market Size and Forecast, 2022-2033(USD Million)
            1. Market Size and Forecast by Product, 2022-2033(USD Million)
            2. Market Size and Forecast by Technology, 2022-2033(USD Million)
            3. Market Size and Forecast by End User, 2022-2033(USD Million)
          2. France Cloning And Mutagenesis Market
            1. France Market Size and Forecast, 2022-2033(USD Million)
              1. Market Size and Forecast by Product, 2022-2033(USD Million)
              2. Market Size and Forecast by Technology, 2022-2033(USD Million)
              3. Market Size and Forecast by End User, 2022-2033(USD Million)
            2. Spain Cloning And Mutagenesis Market
              1. Spain Market Size and Forecast, 2022-2033(USD Million)
                1. Market Size and Forecast by Product, 2022-2033(USD Million)
                2. Market Size and Forecast by Technology, 2022-2033(USD Million)
                3. Market Size and Forecast by End User, 2022-2033(USD Million)
              2. Italy Cloning And Mutagenesis Market
                1. Italy Market Size and Forecast, 2022-2033(USD Million)
                  1. Market Size and Forecast by Product, 2022-2033(USD Million)
                  2. Market Size and Forecast by Technology, 2022-2033(USD Million)
                  3. Market Size and Forecast by End User, 2022-2033(USD Million)
                2. Rest of Europe Cloning And Mutagenesis Market
                  1. Rest of Europe Market Size and Forecast, 2022-2033(USD Million)
                    1. Market Size and Forecast by Product, 2022-2033(USD Million)
                    2. Market Size and Forecast by Technology, 2022-2033(USD Million)
                    3. Market Size and Forecast by End User, 2022-2033(USD Million)
  1. Asia Pacific Cloning And Mutagenesis Market
    1. Asia Pacific Cloning And Mutagenesis Market
      1. Asia Pacific Market Size and Forecast, 2022-2033(USD Million)
        1. Market Size and Forecast by Product, 2022-2033(USD Million)
        2. Market Size and Forecast by Technology, 2022-2033(USD Million)
        3. Market Size and Forecast by End User, 2022-2033(USD Million)
      2. Japan Cloning And Mutagenesis Market
        1. Japan Market Size and Forecast, 2022-2033(USD Million)
          1. Market Size and Forecast by Product, 2022-2033(USD Million)
          2. Market Size and Forecast by Technology, 2022-2033(USD Million)
          3. Market Size and Forecast by End User, 2022-2033(USD Million)
        2. China Cloning And Mutagenesis Market
          1. China Market Size and Forecast, 2022-2033(USD Million)
            1. Market Size and Forecast by Product, 2022-2033(USD Million)
            2. Market Size and Forecast by Technology, 2022-2033(USD Million)
            3. Market Size and Forecast by End User, 2022-2033(USD Million)
          2. India Cloning And Mutagenesis Market
            1. India Market Size and Forecast, 2022-2033(USD Million)
              1. Market Size and Forecast by Product, 2022-2033(USD Million)
              2. Market Size and Forecast by Technology, 2022-2033(USD Million)
              3. Market Size and Forecast by End User, 2022-2033(USD Million)
            2. South Korea Cloning And Mutagenesis Market
              1. South Korea Market Size and Forecast, 2022-2033(USD Million)
                1. Market Size and Forecast by Product, 2022-2033(USD Million)
                2. Market Size and Forecast by Technology, 2022-2033(USD Million)
                3. Market Size and Forecast by End User, 2022-2033(USD Million)
              2. Australia Cloning And Mutagenesis Market
                1. Australia Market Size and Forecast, 2022-2033(USD Million)
                  1. Market Size and Forecast by Product, 2022-2033(USD Million)
                  2. Market Size and Forecast by Technology, 2022-2033(USD Million)
                  3. Market Size and Forecast by End User, 2022-2033(USD Million)
                2. Rest of Asia Pacific Cloning And Mutagenesis Market
                  1. Rest of Asia Pacific Market Size and Forecast, 2022-2033(USD Million)
                    1. Market Size and Forecast by Product, 2022-2033(USD Million)
                    2. Market Size and Forecast by Technology, 2022-2033(USD Million)
                    3. Market Size and Forecast by End User, 2022-2033(USD Million)
  1. Latin America Cloning And Mutagenesis Market
    1. Latin America Cloning And Mutagenesis Market
      1. Latin America Market Size and Forecast, 2022-2033(USD Million)
        1. Market Size and Forecast by Product, 2022-2033(USD Million)
        2. Market Size and Forecast by Technology, 2022-2033(USD Million)
        3. Market Size and Forecast by End User, 2022-2033(USD Million)
      2. Brazil Cloning And Mutagenesis Market
        1. Brazil Market Size and Forecast, 2022-2033(USD Million)
          1. Market Size and Forecast by Product, 2022-2033(USD Million)
          2. Market Size and Forecast by Technology, 2022-2033(USD Million)
          3. Market Size and Forecast by End User, 2022-2033(USD Million)
        2. Mexico Cloning And Mutagenesis Market
          1. Mexico Market Size and Forecast, 2022-2033(USD Million)
            1. Market Size and Forecast by Product, 2022-2033(USD Million)
            2. Market Size and Forecast by Technology, 2022-2033(USD Million)
            3. Market Size and Forecast by End User, 2022-2033(USD Million)
          2. Argentina Cloning And Mutagenesis Market
            1. Argentina Market Size and Forecast, 2022-2033(USD Million)
              1. Market Size and Forecast by Product, 2022-2033(USD Million)
              2. Market Size and Forecast by Technology, 2022-2033(USD Million)
              3. Market Size and Forecast by End User, 2022-2033(USD Million)
            2. Rest of Latin America Cloning And Mutagenesis Market
              1. Rest of Latin America Market Size and Forecast, 2022-2033(USD Million)
                1. Market Size and Forecast by Product, 2022-2033(USD Million)
                2. Market Size and Forecast by Technology, 2022-2033(USD Million)
                3. Market Size and Forecast by End User, 2022-2033(USD Million)
  1. MEA Cloning And Mutagenesis Market
    1. MEA Cloning And Mutagenesis Market
      1. MEA Market Size and Forecast, 2022-2033(USD Million)
        1. Market Size and Forecast by Product, 2022-2033(USD Million)
        2. Market Size and Forecast by Technology, 2022-2033(USD Million)
        3. Market Size and Forecast by End User, 2022-2033(USD Million)
      2. GCC Cloning And Mutagenesis Market
        1. GCC Market Size and Forecast, 2022-2033(USD Million)
          1. Market Size and Forecast by Product, 2022-2033(USD Million)
          2. Market Size and Forecast by Technology, 2022-2033(USD Million)
          3. Market Size and Forecast by End User, 2022-2033(USD Million)
        2. South Africa Cloning And Mutagenesis Market
          1. South Africa Market Size and Forecast, 2022-2033(USD Million)
            1. Market Size and Forecast by Product, 2022-2033(USD Million)
            2. Market Size and Forecast by Technology, 2022-2033(USD Million)
            3. Market Size and Forecast by End User, 2022-2033(USD Million)
          2. Rest of MEA Cloning And Mutagenesis Market
            1. Rest of MEA Market Size and Forecast, 2022-2033(USD Million)
              1. Market Size and Forecast by Product, 2022-2033(USD Million)
              2. Market Size and Forecast by Technology, 2022-2033(USD Million)
              3. Market Size and Forecast by End User, 2022-2033(USD Million)
  1. Competitor Analysis
    1. Market Share Analysis, 2022
    2. Major Recent Developments, 2019-2022
  2. Company Profiles
    1. Jena Bioscience GmbH
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    2. Thermo Fisher Scientific, Inc.
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    3. New England Biolabs
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    4. Merck KGaA
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    5. Promega Corporation
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    6. Bio-Rad Laboratories, Inc.
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    7. Assay Genie
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    8. Takara Bio Inc.
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    9. Agilent Technologies, Inc.
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    10. Danaher
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    11. TransGen Biotech Co., Ltd
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    12. Company 12
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    13. Company 13
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    14. Company 14
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
    15. Company 15
      1. Company Snapshot
      2. Company Overview
      3. Financial Analysis
      4. Product Benchmarking
      5. Recent Developments
  1. Conclusion
  2. Recommendations

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